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中文名稱：錨蛋白重復(fù)結(jié)構(gòu)域蛋白11抗體

英文名稱：Anti-ANKRD11 antibody

上海研盟生物科技有限公司Anti-ANKRD11抗體*，主要應(yīng)用于WB、IHC、IF、ELISA、流式細(xì)胞術(shù)等實(shí)驗(yàn)中。說(shuō)明書隨貨發(fā)送，您也可以直接我司在線客服索取。客服:.

錨蛋白重復(fù)結(jié)構(gòu)域蛋白11抗體,Anti-ANKRD11抗體簡(jiǎn)單介紹：

產(chǎn)品別名：ANCO 1; ANCO1; Ankyrin repeat containing cofactor 1; Ankyrin repeat domain 11; Ankyrin repeat domain containing protein 11; LZ16; T13; ANR11_HUMAN; Ankyrin repeat domain-containing protein 11; Ankyrin repeat-containing cofactor 1.

產(chǎn)品規(guī)格：0.1ml、0.2ml、1ml

產(chǎn)品用途：科研實(shí)驗(yàn)

產(chǎn)品價(jià)格：請(qǐng)報(bào)價(jià)

說(shuō)明書：請(qǐng)?zhí)砑涌头苯铀魅?/p>

抗體來(lái)源：該指標(biāo)有兩種產(chǎn)品，一種是兔來(lái)源抗體，一種是鼠來(lái)源抗體

克隆類型：兔來(lái)源為多克隆抗體，鼠來(lái)源單克隆抗體

交叉反應(yīng)：請(qǐng)索取說(shuō)明書查看

背景介紹：Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 22–24 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases; most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.

錨蛋白重復(fù)結(jié)構(gòu)域蛋白11抗體保存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

性狀：Lyophilized or Liquid

濃度：1mg/1ml

亞型:IgG

純化方法: affinity purified by Protein A

儲(chǔ) 存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol

免疫應(yīng)答過(guò)程：

1.抗原進(jìn)入機(jī)體；

2.抗原刺激 B淋巴細(xì)胞，使之分化增殖成為抗體分泌漿細(xì)胞和記憶細(xì)胞（初次免疫應(yīng)答）；

3.抗體主要由漿細(xì)胞分泌；

4.記憶細(xì)胞再次受到特異性抗原刺激后會(huì)被激活而成為分泌抗體的漿細(xì)胞（再次免疫應(yīng)答）；

5.記憶B細(xì)胞是長(zhǎng)命細(xì)胞，可以存活數(shù)月甚至機(jī)體終生。

初次體液免疫是指宿主*次接觸外來(lái)TD抗原后血清中逐漸出現(xiàn)抗原特異性抗體的過(guò)程。初次體液免疫應(yīng)答的延遲相（從抗原免疫到抗體水平達(dá)到高峰的時(shí)間）為6-10天，起初幾天血清中的抗原特異性抗體主要為親和力較低的IgM,后期以IgG為主。初次應(yīng)答過(guò)程的血清中抗原特異性抗體的高峰濃度較低且維持時(shí)間較短。再次體液免疫應(yīng)答是指曾被某抗原免疫過(guò)的宿主再次接觸該抗原時(shí)血清中迅速出現(xiàn)抗原特異性抗體的過(guò)程，其延遲相僅為4-5天，血清抗體以IgG為主，其高峰濃度較高且維持時(shí)間較長(zhǎng)。再次應(yīng)答所產(chǎn)生的抗體還有親和力成熟現(xiàn)象，即該抗體與抗原的親和力明顯高于初次應(yīng)答產(chǎn)生的抗體。

錨蛋白重復(fù)結(jié)構(gòu)域蛋白11抗體,Anti-ANKRD11抗體相關(guān)產(chǎn)品：

HEV  戊型肝炎病毒抗體
HGF(hepatocyte growth factor)  肝細(xì)胞生長(zhǎng)因子抗體
HGV（Hepatitis G vivus）  庚型肝炎病毒抗體
ZEBRA/HHV4/EBV（Human herpesvirus 4 type 2/epstein-barr virus ）  類皰疹病毒4抗體
HHV8/ORF K2(Human herpesvirus 8)  類皰疹病毒8抗體
HHV8/ORF K2(Human herpesvirus 8)  類皰疹病毒8抗體
HHV8/ORF50(Human herpesvirus 8 type P)  類皰疹病毒8抗體
HHV8/ORF50(Human herpesvirus 8 type P)  類皰疹病毒8抗體
HHV8/ORF K2(Human herpesvirus 8 type P)  類皰疹病毒8抗體
HIF-1α （YMpoxia-inducible factor -1α）  缺氧誘導(dǎo)因子1α 抗體
HIF-1β/ARNT1(YMpoxia-inducible factor -1β)  缺氧誘導(dǎo)因子1β 抗體
HIF-2α （YMpoxia-inducible factor-2α）  缺氧誘導(dǎo)因子2α 抗體
HINT1（histidine triad nucleotide binding protein 1）  *三聚體核苷結(jié)合蛋白1抗體
Histone H3,Family 3A (HISTIH3I protein)  抗組蛋白3抗體
Histone H1  抗組蛋白H1抗體
Histone H1b/Histone H1.4(Ac-Lys53)  抗乙?；M蛋白H1b抗體
Histone H2/HTB901  抗組蛋白H2抗體
Histone H3-like protein  組蛋白H3樣抗體(Brassica juncea)
Histone H3-like protein  組蛋白H3樣抗體（Brassica junceaC端抗體）
Histone H3-like protein  組蛋白H3樣蛋白抗體（Brassica juncea N端抗體）