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聯(lián)系我時,請告知來自 環(huán)保在線研盟生物標(biāo)記抗體“FITC標(biāo)記的組蛋白H3樣抗體“,規(guī)格100ul,保證品質(zhì),咨詢:
【友情提示】:產(chǎn)品價格與說明書請?zhí)砑?,索要說明書;或者!
產(chǎn)品名稱 FITC標(biāo)記的組蛋白H3樣抗體
產(chǎn)品編號 BYK-0483R-FITC
英文名稱 Anti-Centromeric histone H3-like protein-2/FITC
中文名稱 FITC標(biāo)記的組蛋白H3樣抗體
別 名 centromere-specific H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4PIF1_BRAJU.
產(chǎn)品類型 植物抗體
研究領(lǐng)域 腫瘤 免疫學(xué) 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 植物
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Brassica juncea
產(chǎn)品應(yīng)用 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2 N-terminus
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹:Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
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