Mouse Anti-JNK antibody
From:RICKY
Catalog Number : RS-92592R
Quantity size : 0.1ml (dilute with pH7.4 0.01 M PBS or antibody diluent )
Background: JNK is a member of the MAP kinase family. JNK is activated by threonine
and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7.
JNK2 (p54a, SAPK1a), along with JNK and JNK3, is thought to play an important role in
nuclear signal transduction through its environmental stress activation and subsequent
phosphorylation of the nuclear transcription factor p53. JNK3 is a neuron-specific form of c-Jun
N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays
regulatory roles in the signaling pathways of neuronal apoptosis. The JNK pathway is critically
involved in diabetes and levels are abnormally elevated in obesity.
pecificity :
– Anti- JNK is a mouse monoclonal antibody
– specific for JNK of rabbit
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein A affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 42kDa
Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The
lyophilized antibody is stable at room temperature for at least one month and for
greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M
PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for
use in human, therapeutic or diagnostic applications.