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上海瑞齊生物科技有限公司

Rabbit Anti-FSHR

時間:2012-7-17閱讀:538
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Rabbit Anti-FSHR
Catalog Number : HZ288172          Quantity size :   0.1ml (dilute with pH 7.4    0.01 M PBS or antibody diluent )
Background: Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G proteincoupled receptor . FSH binds to the receptor in a hand-clasp fashion via its α and β subunits. While the α subunit of FSH is involved in the binding of FSH to the receptor , the β subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however , this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
pecificity :   
        Anti-FSHR is a rabbit polyclonal antibody unconjugated                 
         specific for FSHR of human, mouse, rat ,goat and sheep         
         use for western blotting,elisa,immunoprecipitation and immunohistochemistry
         Protein G affinity chromatography purification, purity :>95%
         Isotype:  IgG
         mol wt:  75 kDa
Rabbit Anti-FSHR
Application :  
        Western blotting 1:100-500                
         Immunohistochemistry 1:100-500                 
         ELISA 1:500-1000                  
         Optimal working dilutions must be determined by the end user.
Storage: Store at -20 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4
 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Rabbit Anti-FSHR

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