聯(lián)系電話
上海勁馬實(shí)驗(yàn)設(shè)備有限公司
中級(jí)會(huì)員·17年
K0013紡錘菌素二鹽酸/Netropsin dihydrochloride
| 參考價(jià): | 面議 |
具體成交價(jià)以合同協(xié)議為準(zhǔn)- K0013 產(chǎn)品型號(hào)
- 品牌
- 生產(chǎn)商 廠商性質(zhì)
- 上海市 所在地
訪問(wèn)次數(shù)：1443更新時(shí)間：2017-07-16 19:10:29
聯(lián)系我們時(shí)請(qǐng)說(shuō)明是環(huán)保在線上看到的信息，謝謝!
- 聯(lián)系人：
- 馮經(jīng)理
- 電話：
- 021-60521817
- 手機(jī)：
- 13817140470
- 售后：
- 86-021-61107441
- 傳真：
- 86－021－64881400
- 地址：
- 上海市松江區(qū)漕河涇研展路455號(hào)B座
- 個(gè)性化：
- www.shjmsw.com
- 手機(jī)站：
- m.shjmsw.com
- 網(wǎng)址：
- www.shjmsw.com
掃一掃訪問(wèn)手機(jī)商鋪
產(chǎn)品介紹
Description
Biochem/physiol Actions Unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.
Caution Protect from light.
Properties
biological source from Streptomyces netropsis
assay ≥98% （HPLC and TLC）
form powder
color faint yellow
solubility H2O: 1 mg/mL
storage temp. −20°C
Safety
Personal Protective Equipment dust mask type N95 （US）, Eyeshields, Faceshields, Gloves
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
RIDADR UN2811 6.1/PG 3
WGK Germany 3
RTECS DW2973000
References
reference Zimmer, C., et al., Protection of （dA.dT） cluster regions in the DNAase I cleavage of DNA by specific interaction with netropsin. Nucleic Acids Res. 8, 2999-3010, （1980） Abstract
Beerman, T.A., et al., Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes. Biochim. Biophys. Acta 1090, 52-60, （1991） Abstract
Poot, M., et al., Distinct patterns of cell cycle disturbance elicited by compounds interfering with DNA topoisomerase I and II activity. Exp. Cell Res. 218, 326-330, （1995） Abstract
Poot, M., et al., The minor-groove binding DNA-ligands netropsin, distamycin A and berenil cause polyploidisation via impairment of the G2 phase of the cell cycle. Cell Struct. Funct. 15, 151-157, （1990） Abstract
Printable Reviews
Product ReviewsReview This Product
