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上海博研生物工程研究中心
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上海博研生物工程研究中心
Anti-OPGL/RANKL抗體,骨保護(hù)蛋白配體抗體，規(guī)格0.1ml/0.2ml,提供，：.
產(chǎn)品名稱：Anti-OPGL/RANKL抗體,骨保護(hù)蛋白配體抗體
產(chǎn)品編號(hào)：BYK-0747R
產(chǎn)品規(guī)格：0.1ml/0.2ml
產(chǎn)品價(jià)格：請(qǐng)
性 狀：Lyophilized or Liquid
濃 度：1mg/1ml
亞 型：IgG
貯 存：貯存于-20℃.
抗體來源：本公司抗體有兔來源和鼠來源等
克隆類型：兔來源為多抗，鼠來源為單抗
產(chǎn)品類型：一抗
此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫(ELISA)，IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)（可來電索取說明）
此產(chǎn)品本公司有標(biāo)記的一抗出售，相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記
Anti-OPGL/RANKL抗體,骨保護(hù)蛋白配體抗體產(chǎn)品介紹：This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
保存條件: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
重要提示: 本產(chǎn)品提供僅供研究使用，不用于人類治療或診斷.
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