產(chǎn)品名稱：Anti-phospho-ATF2(Ser490/498)抗體,磷酸化活化復(fù)制因子2抗體
產(chǎn)品編號：BYK-1648R
產(chǎn)品規(guī)格：0.1ml/0.2ml
英文名稱 phospho-ATF2 (Ser490/498)
中文名稱 磷酸化活化復(fù)制因子2抗體
別 名 ATF2 (phospho S490); p-ATF2 (phospho S490); ATF2 (phospho S490 + S498); p-ATF2 (phospho S490 + S498); CREB 2; HB 16;Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive.
產(chǎn)品類型 磷酸化抗體
研究領(lǐng)域 腫瘤 免疫學(xué) 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) 細胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源：本公司抗體有兔來源和鼠來源等
克隆類型：兔來源為多抗，鼠來源為單抗
產(chǎn)品類型：一抗
此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫(ELISA)，IF、IP、流式細胞術(shù)等實驗（可來電索取說明）
此產(chǎn)品本公司有標記的一抗出售，相關(guān)標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記
Anti-phospho-ATF2(Ser490/498)抗體,磷酸化活化復(fù)制因子2抗體產(chǎn)品介紹：ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Anti-phospho-ATF2(Ser490/498)抗體,磷酸化活化復(fù)制因子2抗體優(yōu)勢產(chǎn)品：
Anti-caldesmon/smooth muscle /FITC 熒光素標記鈣調(diào)結(jié)合蛋白/鈣調(diào)素結(jié)合蛋白抗體IgG
Anti-Calpain 1/FITC 熒光素標記鈣蛋白酶抗體IgG
Anti-Calpain 2/FITC 熒光素標記鈣蛋白酶2抗體IgG
Anti-Calponin 1/FITC 熒光素標記鈣調(diào)節(jié)蛋白-1抗體IgG
Anti-Camk1g/FITC 熒光素標記鈣/鈣調(diào)蛋白依賴蛋白激酶IG抗體 IgG
Anti-CaMK2a/FITC 熒光素標記鈣/鈣調(diào)素依賴蛋白激酶2α抗體IgG
Anti-CaMK2b/FITC 熒光素標記鈣/鈣調(diào)素依賴蛋白激酶2b抗體IgG
Anti-CANX/FITC 熒光素標記抗鈣連蛋白抗體IgG
Anti-ISR-α/RBITC 紅色熒光素羅丹明標記(RBITC)胰島素受體-α抗體IgG(標記抗體)
Anti-CAP2/FITC 熒光素標記環(huán)化酶相關(guān)蛋白CAP-2抗體IgG
Anti-Cap43/NDRG1 /FITC 熒光素標記分化相關(guān)基因Cap43抗體IgG
Anti-CAS/FITC 熒光素標記細胞凋亡敏感性基因抗體IgG
Anti-Casein/FITC 熒光素標記抗牛酪蛋白抗體IgG
Anti-Caspase-1/FITC 熒光素標記天冬氨酸-*特異性蛋白酶家族抗體IgG
Anti-Caspase-3/RBITC 紅色熒光素羅丹明標記(RBITC)Caspase-3 蛋白抗體(標記抗體)
Anti-Caspase-3 p17 subunit/FITC 熒光素標記Caspase-3 p17 subunit蛋白抗體
Anti-active Caspase 3/FITC 熒光素標記活化半胱胺酸蛋白酶蛋白-3抗體IgG
